540 Highway 17
SAN MATEO, FL 32187

Prime Commercial Opportunity on Highway 17 – Palatka, Florida Position your business for success with this well-maintained commercial building offering 296 feet of high-visibility frontage along one of Palatka’s busiest corridors—U.S. Highway 17. Situated on a generous 1.16-acre parcel, this property provides ample space for parking, expansion, or redevelopment. Located in a high-traffic area with strong visibility, it’s ideal for a wide range of business opportunities and is ready for immediate occupancy. Zoned C-2 (General Commercial), the site allows for a broad variety of permitted uses, including general and food retail sales, professional and medical offices, service-based businesses (excluding tattoo parlors), commercial recreation and entertainment venues, cultural and civic institutions, religious facilities, child and adult day care centers, nursing homes, assisted living facilities, hospitals, and emergency medical services. Additionally, uses such as passenger vehicle services limited to tire, battery, and oil changes, car washes, drive-through facilities, and lodging are also permitted under the current zoning. For those seeking even more flexibility, a Special Use Permit may allow for uses including educational institutions, clubs, essential public services, and expanded religious or drive-through facilities. This is a rare opportunity to secure a versatile and strategically located commercial property in a growing market. Whether you're expanding an existing business or launching a new venture, this location provides excellent visibility, accessibility, and long-term value. Don’t miss out—contact us today to schedule your private tour and explore the full potential of this exceptional property.